 杨敬平博士
副教授
电话：邮箱：jpyang@nju.edu.cn 地址：研究方向：
单细胞多组学、智能基因组学、疾病早期诊断与干预、复杂疾病机制解析 杨敬平 韦德1946体育官方入口副教授，博士生导师 江苏省“双创”人才 | 江苏省优秀青年骨干教师 博士毕业于美国Emory大学 课题组愿景： 致力于“精准解码基因组，为复杂疾病诊疗寻找新钥匙”。我们不只是做基础研究，更直面临床难题。课题组深度融合单细胞多组学、空间转录组、高通量基因组学与先进生物信息学/AI算法，旨在解析细胞命运决定机制，绘制肾脏肿瘤、自身免疫病等复杂疾病的调控图谱，开发早期诊断与干预新策略。 平台与资源： 获国家重点研发计划及多项国家科技项目强力支持，经费充足，设备一流。近年在 Nature Communications, JASN 等国际顶刊发表多项突破性成果。 我们寻找这样的你： 对科学充满好奇与热情； 拥有探索未知的勇气和持之以恒的毅力； 我们看重探索精神胜过现有背景！无论你来自何专业，只要你对生物医学有热情，我们将提供充足的资源与包容的环境，守护你的好奇心，支持你大胆试错与创新，无基础者提供系统培训，期待与你并肩作战，在破解生命密码的征途中，共同收获顶尖的学术成果，也遇见那个更强大、更自信的自己。 联系我们： 中国肾脏生理学会青委会委员 Science、Nature Communications等期刊审稿人 1. Jing Zhang, Zhaojun Liu, Shihui Dong, Kun Xu, Kangchun Wang, Luyu Gong, Qiaoqiao Liu, Yue Guo, Yeping Zhu, Jingrong She, Song Jiang, Shaolin Shi*, Zhihong Liu*, Jingping Yang*, Functional genomics reveals adipose-kidney crosstalk as a contributor to kidney fibrosis via the OSM-OSMR pathway, Funct Integr Genomics, 2025 2. Yue Guo, Jing Zhang, Luyu Gong, Na Liu, Qiaoqiao Liu, Zhaojun Liu, Baosheng Guo*, Jingping Yang*, Mechanical Loading Induces NRF2 Nuclear Translocation to Epigenetically Remodel Oxidative Stress Defense in Osteocytes, Antioxidants, 2025 3. Qi Wang, Bolei Zhang, Yue Guo, Luyu Gong, Erguang*, Jingping Yang*, Unlocking cross-modal interplay of single-cell joint profiling with CellMATE, Brief Bioinform., 2024 4. Ying Xu, Zhidan Xiang, Weigao E, Yue Lang, Sijia Huang, Weisong Qin, Jingping Yang*, Zhaohong Chen*, Zhihong Liu*, Single-cell transcriptomes reveal a molecular link between diabetic kidney and retinal lesions, Communications Biology, 2023 5. Jing Zhang, Zhaohui Ouyang, Limei Xia, Qi Wang, Feng Zheng, Kun Xu, Yuexian Xing, Ke Wei, Shaolin Shi*, Chaojun Li*, Jingping Yang*, Dynamic chromatin landscape encodes programs for perinatal transition of cardiomyocytes, Cell Death Discov., 2023 6. Qi Wang, Yang Zhang, Bolei Zhang, Yao Fu, Xiaozhi Zhao, Jing Zhang, Ke Zuo, Yuexian Xing, Song Jiang, Zhaohui Qin, Erguang Li, Hongqian Guo*, Zhihong Liu*; Jingping Yang*, Single-cell chromatin accessibility landscape in kidney identifies additional cell-of-origin in heterogenous papillary renal cell carcinoma, Nature Communications, 2022 7. Aiping Duan, Hong Wang, Yan Zhu, Qi Wang, Jing Zhang, Qing Hou, Yuexian Xing, Jinsong Shi, Jinhua Hou, Zhaohui S. Qin, Zhaohong Chen, Zhihong Liu*, Jingping Yang*, Chromatin architecture reveals cell type-specific target genes for kidney disease risk variants, BMC Biology, 2021 8. Hong Wang, Aiping Duan, Jing Zhang, Qi Wang, Yuexian Xing, Zhaohui Qin, Zhihong Liu*, Jingping Yang*. Glucocorticoid receptor wields chromatin interactions to tune transcription for cytoskeleton stabilization in podocytes, Commun Biol. 2021 9. Jingping Yang*, Difei Zhang, Masaru Motojima, Tsutomu Kume, Qing Hou, Yu Pan, Aiping Duan, Mingchao Zhang, Song Jiang, Jinhua Hou, Jingsong Shi, Zhaohui Qin, Zhihong Liu*, Super-Enhancer- Associated Transcription Factors Maintain Transcriptional Regulation in Mature Podocytes, JASN, 2021 10. Xiannan Meng, Haoran Peng, Yuanzhen Ding, Ling Zhang, Jingping Yang*, Xiaodong Han*. A transcriptomic regulatory network among miRNAs, piRNAs, circRNAs, lncRNAs and mRNAs regulates microcystin-leucine arginine (MC-LR)-induced male reproductive toxicity. Sci Total Environ. 2019; 667:563-577 2024-2027，科技部 “常见多发病防治研究” 重点研发计划 江苏省“双创”人才 江苏省“青蓝工程”优秀青年骨干教师 |